N-Acetylglucosamine (NAG) is a naturally occurring amino sugar derived from glucose. It is widely used in cosmetic formulations, dietary supplements, and pharmaceutical applications due to its excellent skin-repairing and moisturizing properties.

As a key building block of hyaluronic acid, NAG plays an important role in improving skin hydration, elasticity, and overall skin health.

Key Benefits

• Skin Brightening – Helps reduce hyperpigmentation and improve uneven skin tone
• Deep Hydration – Enhances moisture retention and supports skin barrier function
• Anti-Aging Support – Promotes smoother, firmer-looking skin
• Gentle & Non-Irritating – Suitable for sensitive skin formulations
• Synergistic Effect – Works well with niacinamide for enhanced results

Applications

N-Acetylglucosamine powder is widely used in:

• Skincare Products: creams, serums, lotions, masks
• Functional Supplements: capsules, tablets, powders
• Pharmaceutical Field
• Personal Care Products

Why Choose Us

• Factory Direct Supply – Competitive wholesale pricing
• Stable Quality – Strict QC under cGMP standards
• Custom Packaging – OEM/Private Label available
• Global Export Experience – Support for USA, EU, Korea, Vietnam markets
• Fast Delivery – Reliable logistics solutions

1.Improving skin photoaging: Retinol has excellent antioxidant properties, which can neutralize free radicals in the skin and reduce their damage to the skin. It can also promote the renewal and repair of skin cells, enhance skin barrier function, improve skin moisturizing ability, reduce the appearance of fine lines and wrinkles, and make the skin firmer, brighter, and more radiant.
2.Fine pores: Retinol can promote the normal differentiation of keratinocytes in the skin, making the distribution of keratinocytes more compact, thereby making pores more delicate and the skin more firm and smooth .
3.Anti-aging and anti wrinkle: on the one hand, retinol can prevent the collagen in the dermis from being decomposed and reduce wrinkles; On the other hand, it can also promote the synthesis of collagen in the dermis, improve and fade wrinkles.
4.Acne removal: Retinol has anti-inflammatory effects on the skin, which can inhibit the secretion of sebum from hair follicles, improve the accumulation of keratin in pores, avoid clogged pores, and thus reduce the occurrence of acne and pimples.

5.Whitening: Retinol can accelerate the metabolism of keratinocytes, inhibit melanin production, regulate melanocyte function, reduce melanocyte activity, and prevent melanin from being transported to surface cells, promoting surface cell metabolism, shedding too many melanocytes containing keratin, thus achieving uniform skin color, reducing pigmentation, and reducing spots .

Application of Retinol

1.Improving skin photoaging: Retinol has excellent antioxidant properties that help neutralize free radicals in the skin and reduce their damage to the skin. Free radicals are one of the main causes of skin photoaging, which can damage skin cells and cause the skin to lose elasticity and luster. Retinol can promote the renewal and repair of skin cells, accelerate the renewal of skin cells, and timely repair damaged skin cells, thereby improving the photoaging state of the skin. Retinol can also enhance the skin barrier function and improve the skin’s moisturizing ability.
2.Anti wrinkle: Retinol can prevent the breakdown of collagen in the dermis layer and reduce the formation of wrinkles; On the other hand, it can also promote the synthesis of collagen in the dermis, improve and fade wrinkles..
3.Acne removal: Studies have shown that retinol has anti-inflammatory effects on the skin, inhibiting the secretion of sebum from hair follicles, improving the accumulation of keratin in pores, and avoiding clogged pores. Therefore, the acne removal effect is obvious.
1.Whitening: Retinol is essentially an active agent of vitamin A. Adding retinol to skincare products can promote the metabolism of skin cells, alleviate pigmentation, help repair pigmentation, and brighten skin tone.
2.Exfoliation: Retinol helps to clear dead skin cells, prevent and alleviate pore blockage, and reduce the formation of acne.

Why choose DayNatural’s Retinol ?

1.With over 20 years of international sales experience, we are confident in providing you with high-quality import and export services.
2.Superior Product Quality–We are committed to delivering consistently high-quality products that meet rigorous standards.
3.Excellent Sealing Performance–Our products feature robust sealing, guaranteeing safety and integrity during storage and transportation.
4.We provide customized services for different clients, including packaging, logistics and targeted supply solutions.

1.Tissue repair and regeneration: Extracellular vesicles derived from mesenchymal stem cells possess tissue damage repair and regeneration functions similar to mesenchymal stem cells, and are widely used in research in tissue repair, anti fibrosis, and anti-cancer fields .
2.Improving cognitive impairment: The research progress of stem cell extracellular vesicles has brought new hope for the treatment of Alzheimer’s disease. Stem cell extracellular vesicles administered through the nasal cavity can reduce inflammatory reactions and improve cognitive function .
3.Pain management: Stem cell extracellular vesicles have made progress in the treatment of osteoarthritis, intervertebral disc disease, neuropathic pain, and other forms of chronic pain by promoting tissue repair, reducing inflammatory response, neuroprotection and nerve repair, regulating pain pathways, and other mechanisms to help alleviate pain, promote repair, and reduce inflammatory response .
4. Repair of stretch marks during pregnancy: The use of stem cell extracellular vesicles as a prevention and repair tool has become a hot topic. By promoting skin regeneration, enhancing skin elasticity, and reducing inflammation, extracellular vesicles provide new hope for the repair of stretch marks during pregnancy.
5.Antitumor: Mesenchymal stem cell exosomes have shown potential as potential carriers of biomolecules and drugs in cancer treatment due to their inherent intercellular communication, tumor localization, low toxicity, low immunogenicity, and ability to clear and cross biological barriers .
6.Spinal cord injury repair: Mesenchymal stem cell extracellular vesicles have recently been considered a potential therapeutic intervention for spinal cord injury, controlling immune and inflammatory responses through multiple mechanisms and assisting in repair.
7.Beauty mechanism: Extracellular vesicles can effectively stimulate receptor cells, release cell vitality, promote their regeneration and rebirth, help fade and remove spots, and promote bright and delicate skin; Accelerate the gene expression of type I collagen and type III collagen, promote fibroblast proliferation, collagen synthesis, and repair damaged skin barriers; Inducing macrophages to polarize towards M2 type, thereby reducing their ability to induce inflammatory responses and inhibiting inflammation.

Application of Exosome

1.In the field of medicine, extracellular vesicles derived from mesenchymal stem cells have shown broad application prospects in tissue repair, anti fibrosis, anti-cancer, improvement of cognitive impairment, pain management, stretch mark repair, and other areas. For example, mesenchymal stem cell exosomes can improve cognitive function in Alzheimer’s disease patients through nasal administration, or improve osteoarthritis by promoting chondrocyte migration and proliferation
2.Biopharmaceuticals and Regenerative Medicine: Extracellular vesicles have shown significant therapeutic potential in preclinical studies of neurological and degenerative diseases by carrying various bioactive molecules such as RNA, proteins, and lipids. For example, multiple stem cell-derived exosomes have been shown in animal models to reduce neuronal apoptosis, improve the inflammatory microenvironment, and promote neural function recovery .
3. In vitro diagnostics (IVD): Extracellular vesicles have become an important breakthrough direction in disease diagnosis due to their high stability, low immunogenicity, and fluid circulation characteristics. It can carry biomarkers such as nucleic acids and proteins derived from mother cells, transmit biological information after being taken up by target cells, and accurately reflect the physiological and pathological status of tumor cells and other pathological cells.
4.Consumer healthcare: Extracellular vesicles have shown potential applications in hair loss treatment, brain health, respiratory care, and other areas. For example, extracellular vesicles carry bioactive molecules such as growth factors, RNA, and miRNA, which precisely activate hair follicle cell proliferation and differentiation, assist in hair follicle functional repair, and effectively improve hair loss problems .
5.Tumor therapy: Extracellular vesicles have shown potential as potential carriers of biomolecules and drugs in cancer treatment due to their inherent intercellular communication, tumor localization, low toxicity, low immunogenicity, and ability to clear and cross biological barriers. For example, bioengineered mesenchymal stem cell exosomes can carry various anti-tumor molecules, such as miRNA, drugs, and proteins.
6.Gene therapy: Extracellular vesicles can serve as gene delivery vectors to deliver genetic substances such as DNA, mRNA, or miRNA into target cells, achieving the goal of gene therapy. This method has the advantages of high efficiency, safety, and controllability, providing new ideas for gene therapy.

Why choose DayNatural’s Exosome ?

1.With over 20 years of international sales experience, we are confident in providing you with high-quality import and export services.
2.Superior Product Quality–We are committed to delivering consistently high-quality products that meet rigorous standards.
3.Excellent Sealing Performance–Our products feature robust sealing, guaranteeing safety and integrity during storage and transportation.
4.We provide customized services for different clients, including packaging, logistics and targeted supply solutions.

1.Powerful antioxidant capacity: Psoralen can effectively neutralize free radicals in the body, reduce oxidative stress damage to cells, protect cells from damage, delay the aging process, and promote health and longevity.
2. Promoting skin health and beauty: Psoralen is highly regarded in the field of beauty and skincare, with anti-inflammatory, anti wrinkle, and whitening effects. It can penetrate deep into the skin, inhibit the release of inflammatory factors, reduce skin inflammation, promote collagen synthesis, enhance skin elasticity, reduce the formation of fine lines and wrinkles, while inhibiting the activity of tyrosinase and reducing the production of melanin, achieving the effect of whitening and lightening spots.
3. Regulating the immune system: Psoralol can enhance the activity of immune cells, promote the secretion of immune factors, improve the body’s immune response ability, and regulate immune balance to prevent autoimmune diseases caused by excessive immune reactions.
4.Potential anti-cancer effects: Multiple studies have shown that psoralen can inhibit the proliferation of various cancer cells, induce cancer cell apoptosis, and inhibit tumor angiogenesis, but its anti-cancer effects are still in the research stage.
5. Agricultural application prospects: As a natural plant growth regulator, psoralen can promote plant growth and development, improve crop yield and quality.
6.Safety and stability: Psoralen, as a natural extract, has higher safety and stability compared to synthetic compounds, making it suitable for use on various skin types, especially sensitive skin populations.

Application of Bakuchiol

1.Beauty and skin care: Psoralen is widely used in skin care products, such as face cream, essence, facial mask, etc., because of its antioxidant, anti-inflammatory, anti-aging, whitening, spot whitening, moisturizing and moisturizing effects .
2.Medical Health: Psoralen has shown potential in immune regulation by enhancing immune cell activity, promoting the secretion of immune factors, improving the body’s immune response ability, regulating immune balance, and preventing autoimmune diseases.
3. Anti cancer research: Psoralol has made breakthrough progress in the field of anti-cancer, which can inhibit cancer cell proliferation, induce cancer cell apoptosis, and inhibit tumor angiogenesis. However, its anti-cancer effect is still in the research stage.
4.Agricultural application: As a natural plant growth regulator, psoralen can promote plant growth and development, improve crop yield and quality.

Why choose DayNatural’s Bakuchiol ?

1.With over 20 years of international sales experience, we are confident in providing you with high-quality import and export services.
2.Superior Product Quality–We are committed to delivering consistently high-quality products that meet rigorous standards.
3.Excellent Sealing Performance–Our products feature robust sealing, guaranteeing safety and integrity during storage and transportation.
4.We provide customized services for different clients, including packaging, logistics and targeted supply solutions.

• Boosts Skin Firmness & Density
  Enhances dermal matrix structure and improves skin resilience

• Stimulates GAGs Production
  Promotes glycosaminoglycan synthesis for better hydration and plumpness

• Reduces Fine Lines & Wrinkles
  Visibly smooths skin and improves texture

• Deep Hydration Effect
  Strengthens skin barrier and reduces water loss

• Low Irritation, High Stability
  Suitable for sensitive skin and stable across a wide pH range

Function & Mechanism

PRO-Xylane acts on the skin’s extracellular matrix by stimulating the synthesis of glycosaminoglycans (GAGs), collagen, and structural proteins. This helps:

• Reinforce dermal-epidermal junction (DEJ)

• Improve skin elasticity and density

• Enhance long-term hydration

It functions similarly to retinol in anti-aging performance but with significantly lower irritation and better stability.

Recommended Application

PRO-Xylane Powder is ideal for:

• Anti-aging serums

• Firming creams & lotions

• Eye care products

• Facial masks

• Repair & barrier creams

Recommended Dosage:

• 1% – 5% in cosmetic formulations

Formulation Advantages

• Excellent compatibility with:

  • Hyaluronic Acid

  • Niacinamide

  • Peptides

  • Ceramides

• Easy to formulate (water-soluble)

• Stable under heat and light

• Suitable for premium skincare lines

Packaging & Supply

• Standard Packaging:

  • 1kg / bag

  • 5kg / drum

  • 25kg / drum

• Custom packaging & private label available

Why Choose Derma Reshine PRO-Xylane

• • High purity ≥99%

  • Stable bulk supply

• OEM / ODM support

• Competitive wholesale pricing

• Trusted cosmetic ingredient manufacturer

Palmitoyl Tripeptide-8 is a bioactive lipopeptide designed to address inflammaging, neurogenic irritation, and skin sensitivity, which are key drivers of premature aging.

Core Mechanisms of Palmitoyl Tripeptide-8

1. Anti-Inflammatory Action at the Source

Palmitoyl Tripeptide-8 directly targets inflammatory signaling pathways:

• Inhibits key pro-inflammatory cytokines:
  • IL-6
  • IL-8
  • TNF-α
• In vitro studies show up to 30% reduction in inflammatory mediator expression
• In vivo human tests demonstrate:
  • 52% reduction in erythema area within 48 hours
• Suppresses Substance P release, reducing:
  • Vasodilation
  • Edema
  • Burning and stinging sensations

Result: Calmer skin tone, reduced redness, and improved tolerance for sensitive skin.

2. Skin Barrier Reinforcement

Beyond inflammation control, Palmitoyl Tripeptide-8 strengthens both physical and immune barriers:

• Increases filaggrin synthesis by 17.8%
• Promotes β-defensin secretion, enhancing innate skin immunity
• Reinforces stratum corneum cohesion
• Reduces recurrence of sensitivity and irritation

Stronger barrier function and long-term skin resilience.

3. Enhanced Penetration & Targeted Delivery

• Palmitoyl modification significantly increases lipophilicity
• Compatible with liposome encapsulation systems
• Transdermal penetration efficiency reaches 2.3× that of conventional tripeptides
• Enables targeted delivery into the dermal layer

Higher bioavailability and faster onset of visible benefits.

Stability & Safety Profile

Stability

• Stable under:
  • pH 5.0–7.5
  • Room temperature conditions
• Avoid direct combination with:
  • Strong oxidizing agents
  • Strong acids or bases
  • High concentrations of preservatives
    to prevent activity loss.

Safety

• Verified through in vitro and human testing
• Low irritation potential
• Suitable for sensitive and reactive skin
• Non-comedogenic
• Excellent formulation compatibility with most cosmetic ingredients

Core Chemical Profile & Functional Significance

Synergistic Formulation Combinations

Collagen & Anti-Aging Enhancement

• Vitamin C
• Copper Peptide (GHK-Cu)
• Palmitoyl Tripeptide-8

Boosts collagen synthesis and improves skin firmness.

Barrier Repair & Skin Resilience

• Ceramide NP
• Cholesterol
• Palmitoyl Tripeptide-8

Restores lipid balance and strengthens the skin barrier.

Anti-Inflammatory & Soothing Systems

• Bisabolol
• Madecassoside
• Palmitoyl Tripeptide-8

Ideal for sensitive, post-procedure, or reactive skin formulations.

Main Effects of Palmitoyl Tripeptide-5

1. Promotes Collagen Synthesis

Palmitoyl Tripeptide-5 stimulates fibroblasts to produce collagen by mimicking the skin’s natural growth factors. Collagen is essential for maintaining skin firmness and elasticity, helping to effectively slow down the visible signs of skin aging.

2. Reduces Wrinkles and Fine Lines

By enhancing collagen production and extracellular matrix (ECM) regeneration, Palmitoyl Tripeptide-5 visibly reduces fine lines and deep wrinkles, resulting in smoother, more youthful-looking skin.

3. Improves Skin Elasticity and Firmness

This peptide supports skin cell regeneration and structural repair, strengthening the skin matrix and improving sagging, firmness, and overall elasticity.

4. Antioxidant Protection

Palmitoyl Tripeptide-5 exhibits antioxidant activity, helping to neutralize free radicals and protect the skin from oxidative stress and environmental aggressors that accelerate aging.

5. Strengthens Skin Barrier Function

It helps repair and reinforce the skin barrier, improving moisture retention, reducing transepidermal water loss (TEWL), and alleviating dryness and flaking.

6. Gentle and Skin-Friendly

With excellent skin compatibility, Palmitoyl Tripeptide-5 is suitable for all skin types, including sensitive skin, and can be safely incorporated into daily skincare formulations without irritation.

Scientifically Proven Anti-Aging Efficacy

Based on original research published in high-impact dermatology journals, Palmitoyl Tripeptide-5 demonstrates the following core mechanisms and clinical benefits:

1. “Collagen Loss Brake” Mechanism

Palmitoyl Tripeptide-5 selectively inhibits MMP-1 (matrix metalloproteinase-1), a key enzyme responsible for collagen degradation.

• In vitro inhibition rate: 82.3%

• Reference: Journal of Investigative Dermatology, 2016
  This mechanism significantly reduces collagen breakdown and photoaging damage.

2. Clinical Repair Evidence

In an 8-week clinical study using a formulation containing 2% Palmitoyl Tripeptide-5:

• Redness area reduced by 57%

• Skin barrier function improved by 35%
  These results confirm its effectiveness in skin repair and barrier enhancement.

3. Dual-Pathway Anti-Aging Mechanism

• Blocking collagen degradation

• Promoting ECM regeneration

• Strengthening the microvascular support network
  This multi-dimensional approach delivers long-term anti-aging and skin-repair benefits.

Recommended Application Concentration

• Sensitive skin repair essence: 1%-3%
• Anti-photoaging face cream: 2%-4%
• Medical device dressing: 3%-5%
• Repair and anti-aging powerhouse combination

Acetyl Hexapeptide-8 Powder is a synthetic peptide widely used in cosmetic formulations for reducing fine lines, wrinkle smoothing, and anti-aging applications. Often referred to as a “Botox-like peptide,” it helps relax facial micro-muscle contractions, improving skin appearance and texture.

This peptide is water-soluble, stable under proper conditions, and suitable for incorporation into creams, serums, and lotions, providing targeted anti-wrinkle benefits without invasive procedures.

Technical Background

Acetyl Hexapeptide-8 is a short-chain synthetic peptide designed to mimic naturally occurring neurotransmitter sequences in the skin. Its primary function is to modulate facial expression-induced muscle contractions, reducing the depth of dynamic wrinkles over time.

Derma Reshine provides high-purity Acetyl Hexapeptide-8, ensuring consistent activity, stability, and ease of formulation in cosmetic products.

Applications

• Anti-aging creams and serums

• Wrinkle-reducing skincare formulations

• Facial lifting and firming products

• Sensitive and mature skin care products

• OEM / private label cosmetic formulations

Natural Phycocyanin Powder is a highly pure, natural pigment protein extracted from Spirulina platensis. It is widely used in cosmetic, nutraceutical, and food applications due to its antioxidant, anti-inflammatory, and skin-soothing properties, as well as its vibrant blue color.

Phycocyanin is a water-soluble protein with strong free radical scavenging activity, helping to protect cells from oxidative stress. In cosmetic formulations, it is particularly suitable for anti-aging, skin-calming, and brightening products, while also offering natural coloration for visually appealing products.

Technical Background

Natural Phycocyanin has a delicate protein structure and is sensitive to heat, light, and pH changes, which can affect its color and stability.
Derma Reshine provides optimized Phycocyanin powder grades, ensuring high stability, consistent color, and excellent dispersibility in aqueous formulations, making it easier for formulators to incorporate into creams, gels, serums, or beverages.

Key Benefits

• Natural blue pigment for cosmetic and nutraceutical applications

• Powerful antioxidant and free radical scavenger

• Anti-inflammatory and skin-soothing properties

• Supports skin health and reduces oxidative stress

• High stability and dispersibility in aqueous systems

Applications

• Skincare products: creams, gels, serums

• Anti-aging and soothing formulations

• Nutraceutical beverages and dietary supplements

• Natural colorant for cosmetics and foods

• Functional food products requiring antioxidants

Boswellic Acid is a plant-derived active ingredient with a complex molecular structure. Its performance and stability depend largely on extraction and standardization processes.

Derma Reshine offers Boswellic Acid with flexible specifications, allowing formulators to select suitable grades according to different formulation needs, ensuring consistent quality and reliable cosmetic performance.

Key Benefits

• Soothes irritated and sensitive skin

• Helps reduce redness and skin discomfort

• Anti-inflammatory and calming effects

• Supports skin balance and comfort

• Suitable for sensitive and acne-prone skin

Applications

• Sensitive skin care products

• Anti-acne and calming formulations

• After-sun and post-treatment skincare

• Dermatological and functional skincare

• Daily soothing creams, lotions, and serums